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Study on the Treatment of Primary Lung Cancer in Guang'anmen Hospital
Primary lung cancer is the most common malignant tumor worldwide.
Its morbidity and mortality are the highest in the world.
In the past 30 years, the incidence of lung cancer has been growing fastest in China.
About 4.5 million new cancer patients are diagnosed every year.
Among them, 815,600 cases are lung cancer and the deaths are 714,700.

The high incidence may be closely related to the increase in the pathogenic factors of lung cancer.
1. Bad living habits
2. Iatrogenic factors
3. Genetic factors
4. Immunodeficiency factors
5. Chemical carcinogens

Traditional Chinese Medicine(TCM) believes that the occurrence of lung cancer is related to internal and external causes.
The external cause is the invasion of pathogenic factors, the internal cause is the deficiency of healthy qi.
Sickness due to deficiency, excess caused by deficiency. 
Deficiency of lung qi and deficiency of both qi and yin are the more common types in deficiency (asthenia) syndrome.
Qi stagnation and blood stasis, phlegm coagulation and toxin accumulation are the main types in excessive (sthenia) syndrome.
The lesion is located in the lungs, closely related to the spleen and kidneys.
It's a disease with a deficiency of root and excessive in symptom. 

Considering the cause, for lung cancer, Western medicine and TCM have different treatment ideas: 

Western medicine advocates to combine multidisciplinary comprehensive treatment with individualized treatment.
Surgery, radiotherapy, chemotherapy, molecular targeted therapy and immunotherapy are rational used.
Staging treatment is applied for non-small cell lung cancer and small cell lung cancer.

TCM treatment of lung cancer takes all aspects into consideration.
Combining disease differentiation and syndrome differentiation.
Taking comprehensive TCM treatment. 
Integrating non-medicine treatments.
Supplementing with TCM therapies, which can improve, regulate and prevent lung cancer symptoms

After years of research, Guang 'anmen hospital combined the advantages of TCM and Western treatment.
The "3+X" treatment mode was summarized.
"3" represents the troika of TCM: decoction, patent herbal medicine, and herbal medicine injection.
They are the cornerstone of treatment with " treatment based on syndrome differentiation " as the core.

"X" stands for TCM characteristic technology developed by Guang'anmen Hospital.

For different treatment stages of lung cancer, the corresponding TCM plan is adopted. It can alleviate the adverse reactions caused by treatment and promote the physical and mental recovery of patients.

In recent years, researchers in Guang'anmen Hospital had adopted RCT/cohort research methods.
Intervention measures were based on TCM comprehensive treatment plans at different stages.
Contrasting with pure western medicine treatment at the same stage, it was found that the integrated TCM and western medicine group was better than the pure western medicine treatment group.
It could reduce the two-year recurrence and metastasis rate of non-small cell lung cancer by 6%, and increase the 2-year survival rate by 4%.
The progression-free time of patients with stage IIIA-IV was extended by 1.05 months.
And median survival was extended by 3.47 months.
Not only can it alleviate the adverse effects of radiotherapy, chemotherapy and targeted therapy, it can also reduce the cost burden of patients' medication, hospitalization, etc.

Guang'anmen Hospital's research on TCM for cancer treatment was started in the 1960s. In 1963, the older generation of experts includes Yu Guiqing, Duan Fengwu, Zhang Daizhao. They established China's first TCM oncology department.
In the 1970s, the therapeutic principle of "strengthening healthy qi and fostering the root " was first proposed. And the first TCM cancer clinical research room was established.
After that, several generations of scholars like Piao Bingkui and Sun Guizhi inherited and innovated the theory of " strengthening healthy qi and fostering the root ". They have successively put forward the theories of "consolidating the root and clearing the source" and "regulating qi and detoxification".
According to the different stages of treatment, they proposed TCM protective treatment, TCM loading treatment, TCM consolidation treatment and TCM maintenance treatment, established a comprehensive TCM cancer treatment model and achieved good clinical results.

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